Isuzu Motors Ltd trading as Isuzu is a Japanese commercial vehicles and diesel engine manufacturing company headquartered in Tokyo. Its principal activity is the production, marketing and sale of Isuzu commercial vehicles and diesel engines.

It also has a number of subsidiaries, included Anadolu Isuzu (a Turkish joint venture with Anadolu Group), Sollers-Isuzu (a Russian joint venture with Sollers JSC), SML Isuzu (formerly Swaraj Mazda), Jianxi Isuzu Motors (a Chinese joint venture with Jiangling Motors Company Group), Isuzu Astra Motor Indonesia, Isuzu Malaysia (Isuzu HICOM), Isuzu UK, Isuzu South Africa, Isuzu Philippines, Taiwan Isuzu Motors, Isuzu Vietnam, and Isuzu Motors India. The company was established in 1916. In 1934, the company fused with the carmaker and was renamed Isuzu, after the Isuzu River.

Isuzu has assembly and manufacturing plants in Fujisawa, as well as in the Tochigi and Hokkaidō prefectures. Isuzu-branded vehicles are sold in most commercial markets worldwide. Isuzu’s primary market focus is on commercial diesel-powered truck, buses and construction, while their Japanese competitor Yanmar focuses on commercial-level powerplants and generators.

By 2009, Isuzu had produced over 21 million diesel engines, which can be found in vehicles all over the world.Isuzu diesel engines are used by dozens of vehicle manufacturers, including Ford Motor Company[citation needed] and the Renault–Nissan–Mitsubishi Alliance.